What is a Stronghold?
There are 15 Strongholds in Diablo 4, and each one is roughly the same size.
It can also potentially unlock new side quests once the townsfolk return.

Malnok
The icy Malnok can be found a small distance east of Kyovashad in Fractured Peaks.
This Stronghold is unusually filled with creatures such as Bloodhawks and Thorn Beasts, rather than humanoid enemies.
Tur Dulra
The ruins of Tur Dulra can be found on the west coast of Scosglen.

The watchtower is filled with bandits who you must defeat by destroying their buildings and killing their lieutenants.
After that, find Captain Ezmin and kill her and her followers to conquer the Stronghold itself.
In this Stronghold you must begin by slaying the 4 Cannibal Champions and releasing the prisoners nearby.

Inside you must defeat various miniboss waves before facing Dark Cardinal Maldul to liberate the region.
Alcarnus
Alcarnus is a small Stronghold squished between the two deserts of Kehjistan.
Head straight to the final room of the Stronghold and speak with the Necromancer there.
Afterwards you must defeat Rashta, The Mad Surgeon, and destroy the three Necrotic Masses in the Stronghold.
This Stronghold is filled with deadly spirits, Banshees, and Shambling Corpses.
check that you’re prepared!
Defeat them to conquer the entire Stronghold.
Doing so will prompt the final boss battle of this Stronghold, against Duz’agur, Eriman’s Bane.
Vyeresz
Vyeresz is a small Stronghold located in the far southeast of Hawezar and Sanctuary in general.
This Stronghold is filled with cultists and snakes - not a nice combo.
Find the three Serpent’s Eye shrines and destroy them.
boss Dianthus in the final room of the Stronghold.
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