Avert the dreaded autoupdate
Fallout 4’s"next generation" updategoes live today.
They’re also bringing the game to the Epic Games Store and upgrading it to Steam Deck Verified status.
If you’re similarly concerned, you might want to disable auto-updates right now.

Next, advanced mods may need updating separately, even if F4SE is made compatible.
This can happen if any hooks into the game they use have changed.
Finally, any traditional mods (i.e.
You might want to hold off installing the updates till you know your favourite mods are compatible, then.
Helpfully, the Nexus Mod folk have prepped aguide to disabling auto-updates across several versions of Fallout 4.
(Update:here they are.)
I can’t remember a dang thing about the story.